Subject Objective

To determine the efficacy and safety of the combined use of hyaluronic acid-based dermal implants and narrowband pulsed light technology.

Material and Methods

Twenty-five healthy volunteers aged 35-65 years participated in the study. Five groups of five participants were randomized. Group I underwent comprehensive correction (skin preparation with biorevitalizers, hardware procedures using phototherapy, and volumetric modeling with hyaluronic acid-based products); Group II underwent three hardware procedures using phototherapy; Group III underwent comprehensive correction (skin preparation with biorevitalizers, three hardware procedures using phototherapy); Group IV underwent three hardware phototherapy procedures; and Group V underwent volumetric correction only.

Result

Improvement in skin tone and smoothing of fine wrinkles were observed in all groups, but the most significant reduction in erythema was noted in Groups I and III. Furthermore, skin redness was already reduced after the biorevitalization procedure, before hardware correction. The depth of wrinkles and folds decreased as expected in Groups I and V, and to a lesser extent in Group III. Patients in Group V did not show a significant change in skin tone. Patients in all groups reported improvements across assessment scales, as well as a high level of satisfaction.

Conclusion

The study confirms the safety and efficacy of combining biorevitalizers, hardware technologies, and hyaluronic acid-based fillers in comprehensive skin rejuvenation and quality improvement protocols. Analysis of the obtained results indicates a more pronounced reduction in pigmentation, erythema, and wrinkles in patients who underwent comprehensive correction.

Dr. Anna Amshinskaya is an accomplished specialist in dermatology, cosmetology, and age-related medicine, with extensive participation in leading Russian and international scientific conferences, seminars, roundtables, and master classes. Her active involvement in these platforms reflects her commitment to continuous learning and staying at the forefront of advancements in aesthetic and clinical dermatology.

She specializes in anti-aging and regenerative medicine, offering comprehensive non-surgical facial and body rejuvenation solutions. Her expertise extends to injection cosmetology, advanced hardware-based aesthetic procedures, and the diagnosis and management of dermatovenereological conditions.

With a strong scientific foundation and a patient-centered approach, she combines evidence-based techniques with modern technologies to deliver safe, effective, and natural-looking outcomes. Her dedication to professional development and excellence has established her as a respected practitioner in the field of aesthetic and regenerative medicine.